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Research

The Best Formulations of Cannabis For Breast Cancer Patients

Lemetria Whitehurst

by Lemetria Whitehurst

October 25, 2024 08:00 am ET Estimated Read Time: 9 Minutes
Fact checked by Emily Mullins Medically reviewed by Dr. Abraham Benavides
The Best Formulations of Cannabis For Breast Cancer Patients

Breast cancer is the most common cancer that American women face today. Every year, thousands of people, mostly biological women, are diagnosed. According to recent data, 1 in 8 women and 1 in 1000 men will develop breast cancer sometime in their life.

While survival rates have improved, the journey is still challenging. The National Cancer Institute estimates that in 2024, there will be approximately 310,720 new diagnoses of breast cancer in women.

In recent years, there’s been growing interest in alternative treatments, including the use of cannabis. Research is starting to show that cannabis might offer several benefits for breast cancer patients, such as managing pain, reducing anxiety, and even enhancing the effects of traditional treatments. Additionally, pre-clinical research has shown that certain cannabis and terpene formulations may have antitumor, antiproliferative, and chemosynergistic properties. 

In this article, we’ll explore the best cannabis formulations that could help breast cancer patients, from oils and tinctures to topicals and edibles. Whether you’re a patient or someone supporting a loved one, this guide will provide you with valuable insights into how cannabis might fit into a holistic treatment plan.

The Latest Science on Cannabis and Its Antitumor Properties

According to 2022 research published in the journal Molecules, scientists found that cannabinoids possess significant antitumor properties, offering possible therapeutic benefits for cancer treatment. 

Traditionally, cannabinoids have been used to ease chemotherapy-related symptoms such as nausea, pain, and appetite loss. However, emerging studies suggest that cannabinoids and terpenes may also play a much larger role in cancer care by actively inhibiting tumor growth and spread.

One of the ways cannabinoids may fight cancer is by inducing apoptosis, a process in which cancer cells are programmed to die. This is crucial because cancer cells typically evade natural cell death mechanisms, allowing them to divide (proliferate) uncontrollably. 

In several preclinical studies, cannabinoids demonstrate the ability to trigger apoptosis in breast cancer cells, particularly in the more aggressive forms such as triple-negative breast cancer (TNBC). In this subtype, both natural and synthetic cannabinoids have shown promising results in inhibiting tumor growth.

Another important property of cannabinoids is their potential to inhibit cell proliferation, which is the rapid multiplication of cancer cells that fuels tumor growth. In 2024, research published by the Journal of Cannabis Research found that this particularly occurs due to the ability of cannabis to have an anti-angiogenic effect, which reduces the number of blood vessels feeding the tumors. 

By slowing or stopping these cellular processes, cannabinoids may prevent the cancer from worsening. As a result, cannabinoids may reduce the chances of metastatic development, where cancer spreads to other parts of the body. This ability to block the spread of cancer is vital in improving survival rates for patients.

Understanding Cannabis Formulations

When it comes to cannabis products, not all are created equal. For example, when looking for products, it’s helpful to keep in mind the balance between THC (tetrahydrocannabinol) and CBD (cannabidiol). THC is traditionally known for getting users “high”, but it also has powerful pain-relieving and anti-nausea properties, which can be helpful for breast cancer patients undergoing conventional allopathic treatments. 

On the other hand, CBD, which does not cause any sort of “high” whatsoever, offers anti-inflammatory, anti-anxiety, and pain-relieving benefits. So, when looking for the best cannabis products, be on the lookout for the following terminology, so that you can understand key product differences, which include: 

Full-Spectrum

Full-spectrum cannabis products contain all the natural compounds found in the cannabis plant, including THC, CBD, other cannabinoids, and terpenes. Terpenes are fragrant compounds found in cannabis that not only give the plant its distinctive smell but also contribute to its therapeutic effects. 

According to aggregated research at CannaKeys, medical reviewer Dr. Abraham Benavides writes, “Terpenes with evidence of direct anti-breast cancer effects include myrcene, limonene, and terpinolene. Their mechanisms are similar to cannabinoids, including anti-inflammatory, anti-oxidative stress, Ras-signaling (limonene), induction of multiple pro-apoptotic pathways, anti-angiogenesis, and reducing tumor cell invasion by downregulation of NF-κB-mediated MMP-9 expression (myrcene).” 

These terpenes may also contribute other beneficial effects. For instance, myrcene is known for its sedative properties, which could help with sleep issues, while limonene might provide mood-boosting benefits. This combination creates the “entourage effect,” where these compounds work together synergistically to enhance the healing benefits. 

Dr. Abe adds that new cannnabitriol (CBT) research done in silico (computer-based) is also early but promising for hormone-sensitive breast cancer by directly targeting the estrogen receptor alpha (ER-α). CBT can’t be purchased as an isolate anywhere, but instead is found in whole-plant formulations as a minor cannabinoid in both THC-dominant and 1:1 THC:CBD plants. CBT is also found in male hemp pollen. 

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Broad Spectrum

Broad-spectrum products are similar to full-spectrum but with one key difference—they contain no THC, making them a good option for those who want to avoid the buzz while still benefiting from other cannabinoids and terpenes. 

Isolates

Isolate products contain only a single compound, typically CBD, making them the purest form but without the added benefits of other plant compounds. 

This means you won’t find any helpful terpenes, flavonoids, alkaloids, sulfuric compounds, or any other natural components that are believed to make whole-plant cannabis products more effective.

Top Cannabis Formulations for Breast Cancer Patients

When considering cannabis formulations for breast cancer patients, it’s essential to explore options that cater to various needs, from managing pain to reducing anxiety, nausea, and inflammation. High-CBD formulations are a popular choice because CBD is shown to provide significant relief from pain, anxiety, nausea, and inflammation while protecting neurons and organs. Additionally, studies indicate that CBD may help overcome cancer cells’ resistance to chemotherapy. 

Products like CBD oils, tinctures, and capsules are widely used, offering a gentle yet effective way to manage symptoms. Hemp brands like Charlotte’s Web and Lazarus Naturals offer nationally-legal, high-CBD products that are well-regarded for their quality and consistency, making them suitable options for breast cancer patients seeking relief.

For those looking for a more balanced approach, THC and CBD combinations can be particularly beneficial. A balanced ratio, such as 1:1 THC to CBD, can offer the therapeutic benefits of both cannabinoids while lessening the psychoactive effects of THC. 

This balance can be especially useful for managing more severe pain or nausea, which are common in allopathic cancer treatment. Interestingly, strains such as Harlequin or Pennywise, which naturally have a balanced THC-to-CBD ratio, have been reported to help breast cancer patients with these symptoms.

Topical cannabis products offer a more targeted approach, providing relief from localized pain and inflammation. Both cannabinoids and terpenes can be absorbed through the skin to give potential anti-inflammatory and pain-relieving effects. These products, which include balms, creams, and patches, can be applied directly to the skin where the discomfort is most intense. 

For breast cancer patients experiencing pain due to surgery or radiation treatment, topicals can offer a non-invasive way to alleviate pain without systemic effects. Be sure to look for brands like Papa & Barkley and Mary’s Medicinals which are well-known for their high-quality topical products.

How to Choose the Right Cannabis Product

Choosing the right cannabis product is crucial for breast cancer patients, and this process should begin with a conversation with healthcare providers. It’s important to discuss the use of cannabis with your oncologist or other healthcare professionals to ensure it aligns with your overall treatment plan. 

Unfortunately, not all doctors are knowledgeable about cannabis and are still ingrained with a “reefer madness” ideology, so finding a cannabis-friendly medical professional who is open to alternative therapies makes a big difference. Look for practitioners who are experienced in integrative medicine or who have a background in cannabis therapies to help you make an informed decision. 

You may find a doctor who is happy to give you a medical cannabis recommendation, but isn’t sure how you should optimally take it. In that case, you may then consider visiting a cannabis health coach for a personalized consultation.

When selecting cannabis products, quality and safety should be top priorities. Opt for products from reputable sources that prioritize third-party testing. This testing ensures that the product is free from harmful contaminants, like pesticides and heavy metals, and accurately labeled in terms of cannabinoid content. Label reading is also key, so look for clear information on THC and CBD concentrations, as well as any additional cannabinoids or terpenes present.

And lastly, make sure you start with a low dose and gradually increase it until you find the “sweet spot” that provides relief without unwanted side effects. Keep in mind that different formulations and consumption methods will have different effects, so you may have to experiment to find what works best for you.

Final Takeaways

As a whole, research indicates that cannabis may offer breast cancer patients a promising treatment option for many common symptoms related to the disease and treatment. However, while the potential of cannabis in breast cancer care is becoming increasingly recognized, it’s important to acknowledge that more research and clinical trials are needed before it can be fully understood as a possibly direct anticancer agent. 

Empowering yourself with knowledge is key to navigating the complex landscape of cannabis therapies for breast cancer. By exploring your options, consulting with healthcare providers, and making informed decisions, you can take an active role in your treatment plan. Cannabis can be a valuable component of a holistic breast cancer care strategy, helping to enhance your quality of life as you navigate your journey to recovery.

Note: The content on this page is for informational purposes only and is not intended to be professional medical advice. Do not attempt to self-diagnose or prescribe treatment based on the information provided. Always consult a physician before making any decision on the treatment of a medical condition.

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