Delta-8 vs. Delta-9 vs. Delta-10 THC: What Are the Similarities and Differences?

Under the 2018 Farm Bill, hemp products became more accessible across the United States. Thus, cannabis culture has been ever-expanding. And with compounds like Delta-8, Delta-9, and Delta-10 THC, figuring out which best suits your needs can be overwhelming. Nevertheless, understanding the difference between Delta-8 vs. Delta-9 vs. Delta-10 can help take your medical cannabis use to the next level.

This article will explain the differences and similarities between these cannabinoids so you can choose the right one for your needs. From understanding how they compare to analyzing their effects on the body – let us help cut through all the confusion surrounding these THC varieties. 

What Is Delta-8 THC?

According to findings in the 2022 Journal for Cannabis Research, delta-8 THC is a hemp-derived product gaining popularity due to its unique characteristics and benefits. The product is created from hemp CBD extract and contains synthesized versions of THC and a mix of related, psychoactive cannabinoids. 

Delta-8 differs from other forms of THC because it binds less strongly with the receptors, meaning that it generally produces milder highs while still providing healing properties. For example, these characteristics make delta-8 THC practical in several therapeutic uses, including managing pain and spasticity, improving appetite, and reducing nausea. While delta-8 carries a milder psychoactive effect than ‘normal THC,’ it still produces an experience that can alter mood and perception. 

With lower levels of intoxication, users may feel more at ease during their experience while feeling energized and mentally focused. As a result, delta-8 is an excellent option for those seeking a more relaxed experience versus a full-throttle experience of traditional marijuana products. It is also a perfect choice for those sensitive to THC’s effects or need more clarity for daytime relief.

Benefits

While there is less data about the health benefits of delta-8 THC, they’re thought to be fairly similar to those of delta-9 THC, which can be used to help with countless conditions and ailments. Also because delta-8 induces less psychoactivity than delta-9, many people who want all of these benefits without a super strong high turn toward delta-8.

Risks

Delta-8 THC exists naturally in the cannabis plant in very small amounts. As such, it often has to be synthesized using other cannabinoids, like CBD. Oftentimes, these manufactured delta-8 products are not been evaluated or approved by the FDA. So, when purchasing delta-8 products, always use caution, buy from a trusted source, and ask for a Certificate of Analysis for every purchase you make.

What Is Delta-9 THC?

Delta-9 THC, also known as delta-9 tetrahydrocannabinol, is one of the most popular cannabinoids. It is highly regulated, often illegal, and is the subject of much discussion in recent years. It is the most abundant and potent psychoactive component in marijuana, accounting for approximately 20-30% of its active ingredients. Therefore, it contributes to the feeling of “high” or relaxation people experience after consuming cannabis products.

Delta-9 THC also interacts with cannabinoid receptors in your brain to produce various psychological effects. When taken carefully and appropriately, users can enjoy significant health benefits from delta-9 THC. 

Delta 9 THC occurs naturally in cannabis plants to varying degrees. It can also be synthesized from the CBD in hemp to make hemp-derived delta 9 THC that works in the same way. It’s technically legal this way, but is debated state by state with certain bans in place.

Benefits

The benefits of delta-9 THC are seemingly countless — and they’ve been studied for years, though bigger, more comprehensive studies are still needed to confirm these potential benefits.

However, delta-9 THC has the potential to offer numerous therapeutic benefits, including but not limited to:

• Nausea and Vomiting  Due to Chemotherapy
• Muscle Spasms and Spasticity
• Chronic Pain
• Increasing Appetite
• Insomnia and Sleep Quality
• Inflammation

Risks

Delta-9 is the most well-known psychoactive compound in cannabis. As such, this psychoactive high can feel overwhelming for beginners, those with a low cannabis tolerance, or those who (accidentally) take a larger dose than they’re used to. Getting too high — or greening out — may cause adverse effects like anxiety, paranoia, dehydration, or severe cognitive impairment.

Additionally, if you choose to combust your cannabis, smoking naturally puts you at risk for respiratory issues from the tar and toxins.

What Is Delta-10 THC?

Delta-10 THC has been getting much attention from the cannabis community lately, but what exactly is it? While it differs slightly in molecular structure from regular delta-9 THC, when ingested, delta-10 can produce many of the same effects associated with traditional delta-9 THC, such as relaxation and mood enhancement.

Some cannabis connoisseurs report it creates a more clear-headed high than typical delta-9. However, due to its weaker ability to bind to CB1 receptors, delta-10 THC tends to produce milder effects. Some users say delta-10’s results are similar to sativas compared to indicas, usually with less anxiety and paranoia.

Benefits

While research on Delta-10 THC is still emerging, it is believed to offer several potential benefits. Just like delta-8, delta-10 THC has less powerful psychoactive effects, which allows patients to take a higher dose without the intense high. Specifically, delta-10 is thought to improve focus and enhance mood, as well as potentially provide some physical benefits like nausea relief and increased appetite.

Risks

Delta-10 is a relatively new and less-studied cannabinoid, so its full risk profile is not yet fully understood. And, just like delta-8, delta-10 only naturally exists in trace amounts in the cannabis plant. As such, it is often manufactured using hemp-derived CBD. So, always make sure you’re purchasing from a trusted source.

What Are the Similarities and Differences Between Delta-8, Delta-9, and Delta-10 THC?

While delta-8, delta-9, and delta-10 THC are all part of the same family of cannabinoids, they are unique in their own ways. Surprisingly, each has a similar molecular structure with only a slight difference in the arrangement of atoms. In fact, the only variation between deltas-8 and 9 is the existence of a double bond between two carbon atoms. 

Each cannabinoid has an array of carbon atoms, with delta-8 having the double bond attached to the eighth carbon, while delta-9 has the double bond attached to the ninth carbon. This distinction gives each compound unique effects on the body when consumed. 

There is a great deal of difficulty in manufacturing delta-10 THC. Refining it is extensive, making it rarer than the other counterparts. Similar to delta 8 THC, delta 10 must be synthesized from the CBD in hemp to meet mass consumer demand. 

The well-documented therapeutic benefits of cannabinoids are also likely present in each delta, although in different quantities and with clinical research yet to be done on delta 8 and 10. However, any of these versions of THC can cause a person to experience both positive and negative effects caused by overconsumption. 

Importantly, semisynthetic cannabinoids like delta 8 and 10 are messy to create, and can have both known and unknown byproducts that may have short and long-term health risks if not made carefully. Buying from a high-quality and trusted source is very important, but we still don’t fully understand all the possible health risks involved.

In addition, compared to delta-9, delta-8 has half the psychoactive effect, offering a more energetic high that uplifts the user’s mood rather than an intense head high. On the flip side, delta-10 is even less psychoactive than its predecessors, delivering a moderate head buzz alongside therapeutic benefits. 

Will Delta-8 and Delta-10 Show Up on a Drug Test?

Simply put, yes, these cannabinoids might show up on a drug test, given that THC appears in the compound name. Urine sample testing is the most commonly used method employed to detect the presence of delta-9 THC, but it can also pick up metabolites from delta-8 and even delta-10 in users’ systems. 

As savvy cannabis users, it’s always important to keep in mind that any form of THC may be detected in a drug test, so use it with caution. 

When to Use Delta-8 vs. Delta-9 vs. Delta-10

Delta-8, 9, and 10 contain different strengths of cannabinoids, so they are helpful in different situations. For instance, delta-9 is known to be the strongest of the three in terms of effects, so it might make sense to use it when aiming for an intense high or when trying to reap the maximum therapeutic benefits.

Choosing delta-8 or 10 might be better suited for more mild goals. For example, for users who prefer a more subtle feeling of euphoria when high, delta-8 may be the best choice. With delta-10, you can achieve a milder high. These deltas can serve as a middle ground between CBD and delta-9 THC, providing a more mellow experience.

Final Thoughts

Ultimately, the main difference between delta-8, delta-9, and delta-10 THC is potency and legality. When deciding which one to use, it is essential to consider the degree of effect you want and your local laws. While delta-8 seems like a reasonable choice as it has similar effects as delta-9 while remaining legal in most parts of the US, users should keep in mind that it can still cause impairment.

Plus, depending on individual preferences or medical conditions, some may find delta-9 or even delta-10 to be a better fit. If you’re feeling adventurous, you can always take advantage of different combinations of all three if your state allows. Choosing new types of cannabis is an experiment, so results will vary for each person.

Frequently Asked Questions

Is Delta-10 stronger than Delta-9?

No, delta-10 induces milder psychoactive effects, compared with delta-9 THC.

Which delta is best for anxiety?

Delta-8 and delta-10 produce milder psychoactive effects than delta-9. As such, both of these cannabinoids are great for achieving that euphoric feeling without the anxiety and paranoia that sometimes accompanies the delta-9 high.

Which delta is best for depression?

Delta-8 and delta-10 both produce fuzzy, euphoric highs that are a bit milder than delta-9-induced psychoactivity. As such, they’re both optimal for patients struggling with depression who may experience anxiety with high-THC products.

What is the best psychoactive delta?

Each cannabis user’s experience is different, and, therefore, individuals often have to experiment a little before choosing which psychoactive delta is best for them. However, delta-9 THC is the most well-researched, and, therefore, the safest (for now).

Note: The content on this page is for informational purposes only and is not intended to be professional medical advice. Do not attempt to self-diagnose or prescribe treatment based on the information provided. Always consult a physician before making any decision on the treatment of a medical condition.

This article was originally published in March 2023 and was most recently updated in June 2024.